Nasal spray therapies are gaining significant traction due to their ability to bypass the blood-brain barrier, which normally prevents many drugs from entering the central nervous system. Traditional methods of drug delivery, such as oral or intravenous, often fail to reach the brain effectively because the molecules are too large. Nasal sprays, however, provide a direct route, allowing medications like Narcan—used to reverse drug overdoses—to be administered rapidly and effectively, even when a person’s circulatory system is compromised.

In recent years, advancements have expanded the scope of nasal sprays beyond emergency medicine. Researchers are now exploring the potential of nasal delivery systems for treating various conditions, including cancers like glioblastoma. By utilizing nanoparticle-sized drugs, nasal sprays offer a less toxic and more targeted approach to treating brain tumors, providing hope for both children and adults suffering from these conditions. Nasal vaccines and therapies for Alzheimer’s disease are also being developed to leverage the immune response in the nasal mucosa and break down harmful brain plaques.

While not all nasal sprays require temperature-controlled transport, certain biologics and immunotherapies do. This is where companies like Thermal Custom Packaging (TCP) come in, offering solutions for ultra-cold transport, ensuring the safety and efficacy of these temperature-sensitive medications as they reach patients in need.